资源类型

期刊论文 1916

年份

2024 3

2023 100

2022 148

2021 144

2020 118

2019 136

2018 123

2017 115

2016 96

2015 111

2014 108

2013 69

2012 89

2011 74

2010 75

2009 51

2008 75

2007 86

2006 35

2005 26

展开 ︾

关键词

风险分析 9

分析 4

可持续发展 4

对策 4

影响因素 4

数值模拟 4

隧道 4

ANSYS 3

COVID-19 3

医院中子照射器I型堆 3

数值分析 3

裂缝 3

2035年 2

BNLAS 2

DX桩 2

HIV感染孕产妇 2

仿真 2

制造业 2

制造强国 2

展开 ︾

检索范围：

排序： 展示方式：

Approaching the binding between Cu(II) and aerobic granules by a modified titration and µ-XRF

Hongwei LUO,Longfei WANG,Zhonghua TONG,Hanqing YU,Guoping SHENG

《环境科学与工程前沿（英文）》 2016年 第10卷 第2期   页码 362-367 doi: 10.1007/s11783-015-0803-0

摘要： Interactions between metals and activated sludge can substantially affect the fate and transport of heavy metals in wastewater treatment plants. Therefore, it is important to develop a simple, fast and efficient method to elucidate the interaction. In this study, a modified titration method with a dynamic mode was developed to investigate the binding of Cu(II), a typical heavy metal, onto aerobic granules. The titration results indicated that pH and ionic strength both had a positive effect on the biosorption capacity of the granular sludge. The -XRF results demonstrated that the distribution of metals on the granular surface was heterogeneous, and Cu showed strong correlations and had the same “hot spots” positions with other metal ions (e.g., Ca, Mg, Fe etc.). Ion exchange and complexing were the main mechanisms for the biosorption of Cu(II) by aerobic granules. These results would be beneficial for better understanding of Cu(II) migration and its fate in wastewater treatment plants.

关键词： aerobic granules     Cu(II)     modified titration     µ-XRF analysis    

HTML PDF 收藏

Thermogravimetric kinetic analysis of

SUKARNI,SUDJITO,Nurkholis HAMIDI,Uun YANUHAR,I.N.G. WARDANA

《能源前沿（英文）》 2015年 第9卷 第2期   页码 125-133 doi: 10.1007/s11708-015-0346-x

摘要： The thermal behavior of combustion in air atmosphere were investigated by performing experiments on STA PT1600 Thermal Analyzer at heating rates of 10°C/min, 40°C/min and 70°C/min and range of temperatures from room temperature to 1200°C. The kinetic parameters were evaluated by using Kissinger and Ozawa methods. The result showed that combustion occurred in five stages. Started with initial devolatilization, the main thermal decomposition and combustion process, transition stage, the combustion of char and the last stage was the slow burning reaction of residual char. In line with increasing heating rate, the mass loss rate increased as well, but it delayed the thermal decomposition processes toward higher temperatures. The average activation energy at the main thermal decomposition stage and the stage of char combustion were approximately 251 kJ/mol and 178 kJ/mol, respectively.

关键词： Nannochloropsis oculata     combustion     kinetic parameters     air atmosphere     thermogravimetric    

HTML PDF 收藏

Genomic and metabolomic analysis of with enhanced poly--glutamic acid production through atmospheric

《化学科学与工程前沿（英文）》 2022年 第16卷 第12期   页码 1751-1760 doi: 10.1007/s11705-022-2211-x

摘要： Poly-γ-glutamic acid is an extracellular polymeric substance with various applications owing to its valuable properties of biodegradability, flocculating activity, water solubility, and nontoxicity. However, the ability of natural strains to produce poly-γ-glutamic acid is low. Atmospheric and room temperature plasma was applied in this study to conduct mutation breeding of Bacillus licheniformis CGMCC 2876, and a mutant strain M32 with an 11% increase in poly-γ-glutamic acid was obtained. Genome resequencing analysis identified 7 nonsynonymous mutations of ppsC encoding lipopeptide synthetase associated with poly-γ-glutamic acid metabolic pathways. From molecular docking, more binding sites and higher binding energy were speculated between the mutated plipastatin synthase subunit C and glutamate, which might contribute to the higher poly-γ-glutamic acid production. Moreover, the metabolic mechanism analysis revealed that the upregulated amino acids of M32 provided substrates for glutamate and promoted the conversion between L- and D-glutamate acids. In addition, the glycolytic pathway is enhanced, leading to a better capacity for using glucose. The maximum poly-γ-glutamic acid yield of 14.08 g·L–1 was finally reached with 30 g·L–1 glutamate.

关键词： ARTP mutagenesis     Bacillus licheniformis     poly-γ-glutamic acid     metabolomics    

HTML PDF 收藏

CeO doping boosted low-temperature NH-SCR activity of FeTiO catalyst: A microstructure analysis and reaction

《环境科学与工程前沿（英文）》 2022年 第16卷 第5期 doi: 10.1007/s11783-022-1539-2

摘要：

• CeO2 doping significantly improved low-temperature NH3-SCR activity on FeTiOx.

关键词： NH3-SCR     CeO2 doping     Low-temperature NOx removal     Improved redox property     In situ XAFS analysis    

HTML PDF 收藏

Analysis of flow over backward facing step with transition

Dwarikanath RATHA,Arindam SARKAR

《结构与土木工程前沿（英文）》 2015年 第9卷 第1期   页码 71-81 doi: 10.1007/s11709-014-0270-x

摘要： The present study deals with the study of the velocity distribution and the separation phenomenon of flow of air over a two dimensional backward facing step. The flow of air over a backward facing step has been investigated numerically using FLUENT. Flow simulation has been carried out in a backward facing step having an expansion ratio (ratio of the height before and after the step) of 1:1.94 and the results obtained are compared with the published experimental results. Comparison of flow characteristics between steps with three different transitions is made. The variation of reattachment length for all the three cases are analyzed for wide range of Reynolds number ranging from 100 to 7000 which covers the laminar, transition and turbulent flow of air. Simulation of the flow over steps with expansion ratios of 1:1.24, 1:1.38, 1:1.47, 1:1.53, 1:1.94, 1:2.20 are also carried out to examine the effect of different expansion ratios on the reattachment length. It is found that the primary reattachment length increases with increase in the expansion ratio. The primary reattachment length at the bottom wall downstream of the step is minimum for the step with round edged transition and maximum for the step with a vertical drop transition.

关键词： Reattachment length     backward facing step     transition     flow separation     k-? model    

HTML PDF 收藏

A systematic approach in load disaggregation utilizing a multi-stage classification algorithm for consumer electrical appliances classification

Chuan Choong YANG, Chit Siang SOH, Vooi Voon YAP

《能源前沿（英文）》 2019年 第13卷 第2期   页码 386-398 doi: 10.1007/s11708-017-0497-z

摘要： The potential to save energy in existing consumer electrical appliances is very high. One of the ways to achieve energy saving and improve energy use awareness is to recognize the energy consumption of individual electrical appliances. To recognize the energy consumption of consumer electrical appliances, the load disaggregation methodology is utilized. Non-intrusive appliance load monitoring (NIALM) is a load disaggregation methodology that disaggregates the sum of power consumption in a single point into the power consumption of individual electrical appliances. In this study, load disaggregation is performed through voltage and current waveform, known as the - trajectory. The classification algorithm performs cropping and image pyramid reduction of the - trajectory plot template images before utilizing the principal component analysis (PCA) and the -nearest neighbor ( -NN) algorithm. The novelty of this paper is to establish a systematic approach of load disaggregation through - trajectory-based load signature images by utilizing a multi-stage classification algorithm methodology. The contribution of this paper is in utilizing the “ -value,” the number of closest data points to the nearest neighbor, in the -NN algorithm to be effective in classification of electrical appliances. The results of the multi-stage classification algorithm implementation have been discussed and the idea on future work has also been proposed.

关键词： load disaggregation     voltage-current (V-I) trajectory     multi-stage classification algorithm     principal component analysis (PCA)     k-nearest neighbor (k-NN)    

HTML PDF 收藏

Elasto-plastic fatigue crack growth analysis of plane problems in the presence of flaws using XFEM

SHEDBALE,I. V. SINGH,B. K. MISHRA

《结构与土木工程前沿（英文）》 2015年 第9卷 第4期   页码 420-440 doi: 10.1007/s11709-015-0305-y

摘要： In this paper, elasto-plastic XFEM simulations have been performed to evaluate the fatigue life of plane crack problems in the presence of various defects. The stress-strain response of the material is modeled by Ramberg-Osgood equation. The von-Mises failure criterion has been used with isotropic hardening. The -integral for two fracture modes (mode-I and mode-II) is obtained by decomposing the displacement and stress fields into their symmetric and antisymmetric parts, then individual stress intensity factors are extracted from -integral. The fatigue life obtained by EPFM is found quite close to that obtained by LEFM.

关键词： XFEM     von-Mises yield criterion     isotropic hardening     fatigue crack growth     J-integral    

HTML PDF 收藏

802.11i认证协议可验安全性形式化分析

宋宇波,胡爱群,姚冰心

《中国工程科学》 2010年 第12卷 第1期   页码 67-73

摘要：

IEEE 802.11标准组提出了802.11i标准以增强无线局域网的安全性能。在802.11i标准中采用了802.1X标准实现无线局域网用户的认证和接入控制过程。针对802.1X认证协议的三方交互结构提出一种扩展Bellare-Rogaway模型，对802.11i认证和密钥交换机制进行可验安全性分析。通过分析，证明802.11i认证协议存在缺陷并给出了相应的中间人攻击方法。

关键词： 802.11i     Bellare-Rogaway模型     可验安全性     形式化分析    

HTML PDF 收藏

Analysis of antibiotic resistance of

Yangyang Yu, Xiaolin Zhu, Guanlan Wu, Chengzhi Wang, Xing Yuan

《环境科学与工程前沿（英文）》 2019年 第13卷 第3期 doi: 10.1007/s11783-019-1123-6

摘要：

The concentrations of four types of antibiotics in the Yitong River were detected.

The concentration of total coliforms in summer was higher than that in spring.

There was a seasonal difference in antibiotic resistance of E. coli.

The E. coli in the Yitong River was found to have multiple antibiotic resistance.

关键词： Yitong River     Coliform bacteria     Antibiotic resistance     Escherichia coli    

HTML PDF 收藏

Life-cycle assessment and techno-economic analysis of the production of wood vinegar from stem: a case

《化学科学与工程前沿（英文）》 2023年 第17卷 第8期   页码 1109-1121 doi: 10.1007/s11705-022-2296-2

摘要： This research undertook a case study of the life-cycle assessment and techno-economic analysis of the slow pyrolysis of Eucommia stem for the production of wood vinegar and activated carbon. The results showed that the production of one ton of wood vinegar via the slow pyrolysis of Eucommia stem show comparatively low global warming potential (2.37 × 102 kg CO2 eq), primary energy demand (3.16 × 103 MJ), acidification potential (2.19 kg SO2 eq), antimony depletion potential (3.86 × 10–4 kg antimony eq), and ozone depletion potential (7.46 × 10–6 kg CFC-11 eq) and was more environmentally friendly than the production of dilute acetic acid (12 wt %) via petrochemical routes. Meanwhile, the total capital investment, total product cost, and cash flowsheet were provided in the techno-economic analysis. Then, the net present value, internal rate of return, and dynamic payback period of the production process were evaluated. The findings indicated that while this production process is cost-effective, it might not be economically attractive or could generate investment risks. An increase in the added value of the wood vinegar and the activated carbon could remarkably improve the economic feasibility of this production process.

关键词： life-cycle assessment     techno-economic analysis     wood vinegar     activated carbon     Eucommia    

HTML PDF 收藏

Regulatory mechanism and functional analysis of

null

《医学前沿（英文）》 2017年 第11卷 第1期   页码 87-96 doi: 10.1007/s11684-016-0469-4

摘要：

S100A9, a calcium-binding protein, participates in the inflammatory process and development of various tumors, thus attracting much attention in the field of cancer biology. This study aimed to investigate the regulatory mechanism of and its function involvement in APL. We used real-time quantitative PCR to determine whether PML/RARα affects the expression of in NB4 and PR9 cells upon ATRA treatment. ChIP-based PCR and dual-luciferase reporter assay system were used to detect how PML/RARα and PU.1 regulate promoter activity. CCK-8 assay and flow cytometry were employed to observe the viability and apoptosis of NB4 cells when was overexpressed. Results showed that was an ATRA-responsive gene, and PML/RARα was necessary for the ATRA-induced expression of in APL cells. In addition, PU.1 could bind to the promoter of , especially when treated with ATRA in NB4 cells, and promote its activity. More importantly, overexpression of induced the apoptosis of NB4 cells and inhibited cell growth. Collectively, our data indicated that PML/RARα and PU.1 were necessary for the ATRA-induced expression of in APL cells. Furthermore, promoted apoptosis in APL cells and affected cell growth.

关键词： S100A9 S100A9     PU.1     PML/RARα     ATRA     APL    

HTML PDF 收藏

Application of StrucGP in medical immunology: site-specific -glycoproteomic analysis of macrophages

《医学前沿（英文）》 2023年 第17卷 第2期   页码 304-316 doi: 10.1007/s11684-022-0964-8

摘要： The structure of N-glycans on specific proteins can regulate innate and adaptive immunity via sensing environmental signals. Meanwhile, the structural diversity of N-glycans poses analytical challenges that limit the exploration of specific glycosylation functions. In this work, we used THP-1-derived macrophages as examples to show the vast potential of a N-glycan structural interpretation tool StrucGP in N-glycoproteomic analysis. The intact glycopeptides of macrophages were enriched and analyzed using mass spectrometry (MS)-based glycoproteomic approaches, followed by the large-scale mapping of site-specific glycan structures via StrucGP. Results revealed that bisected GlcNAc, core fucosylated, and sialylated glycans (e.g., HexNAc4Hex5Fuc1Neu5Ac1, N4H5F1S1) were increased in M1 and M2 macrophages, especially in the latter. The findings indicated that these structures may be closely related to macrophage polarization. In addition, a high level of glycosylated PD-L1 was observed in M1 macrophages, and the LacNAc moiety was detected at Asn-192 and Asn-200 of PD-L1, and Asn-200 contained Lewis epitopes. The precision structural interpretation of site-specific glycans and subsequent intervention of target glycoproteins and related glycosyltransferases are of great value for the development of new diagnostic and therapeutic approaches for different diseases.

关键词： macrophage     glycoproteome     glycopeptides     N-glycan structures     PD-L1    

HTML PDF 收藏

Panoramic variation analysis of a family with neurodevelopmental disorders caused by biallelic loss-of-function

《医学前沿（英文）》 doi: 10.1007/s11684-023-1006-x

摘要： Highly clinical and genetic heterogeneity of neurodevelopmental disorders presents a major challenge in clinical genetics and medicine. Panoramic variation analysis is imperative to analyze the disease phenotypes resulting from multilocus genomic variation. Here, a Pakistani family with parental consanguinity was presented, characterized with severe intellectual disability (ID), spastic paraplegia, and deafness. Homozygosity mapping, integrated single nucleotide polymorphism (SNP) array, whole-exome sequencing, and whole-genome sequencing were performed, and homozygous variants in TMEM141 (c.270G>A, p.Trp90*), DDHD2 (c.411+767_c.1249-327del), and LHFPL5 (c.250delC, p.Leu84*) were identified. A Tmem141p.Trp90*/p.Trp90* mouse model was generated. Behavioral studies showed impairments in learning ability and motor coordination. Brain slice electrophysiology and Golgi staining demonstrated deficient synaptic plasticity in hippocampal neurons and abnormal dendritic branching in cerebellar Purkinje cells. Transmission electron microscopy showed abnormal mitochondrial morphology. Furthermore, studies on a human in vitro neuronal model (SH-SY5Y cells) with stable shRNA-mediated knockdown of TMEM141 showed deleterious effect on bioenergetic function, possibly explaining the pathogenesis of replicated phenotypes in the cross-species mouse model. Conclusively, panoramic variation analysis revealed that multilocus genomic variations of TMEM141, DDHD2, and LHFPL5 together caused variable phenotypes in patient. Notably, the biallelic loss-of-function variants of TMEM141 were responsible for syndromic ID.

关键词： neurodevelopmental disorder     autosomal recessive intellectual disability     consanguinity     spastic paraplegia     hearing loss     TMEM141    

HTML PDF 收藏

Development of a new method for RMR and Q classification method to optimize support system in tunneling

Asghar RAHMATI,Lohrasb FARAMARZI,Manouchehr SANEI

《结构与土木工程前沿（英文）》 2014年 第8卷 第4期   页码 448-455 doi: 10.1007/s11709-014-0262-x

摘要： Rock mass classification system is very suitable for various engineering design and stability analysis. classification method is confirmed by Japan Highway Public Corporation that this method can figure out either strength or deformability of rock mass, further appropriating the amount of rock bolts, thickness of shotcrete, and size of pitch of steel ribs just after the blasting procedure. Based on these advantages of method, in this study, according to data of five deep and long tunnels in Iran, two equations for estimating the value of method from and classification systems were developed. These equations as a new method were able to optimize the support system for and classification systems. From classification and its application in these case studies, it is pointed out that the method for the design of support systems in underground working is more reliable than the and classification systems.

关键词： JH classification     Q and RMR classification     new method    

HTML PDF 收藏

抗白粉病基因 <i>Pm40i> 在我国“后 <i>Pm21i> 时代”小麦育种中的重要作用 Perspective

唐圣雯,胡玉亭,钟胜福,罗培高

《工程（英文）》 2018年 第4卷 第4期   页码 500-506 doi: 10.1016/j.eng.2018.06.004

摘要：

由小麦白粉菌[Blumeria graminis f. sp. tritici（Bgt）] 引起的小麦白粉病是一种重要的小麦叶部病害，对小麦的产量产生很大的影响。20 世纪80 年代，通过簇毛麦（Heuchera villosa）的6VS 染色体与小麦6AL 染色体易位将抗白粉病基因Pm21 转移到普通小麦中。最近，在一些地方发现了对Pm21 有毒的Bgt，虽然这些菌株的病理学特性还有待研究，但这一现象提醒小麦育种者应注意应用Pm21 的风险。来源于普通小麦与中间偃麦草（Thinopyrum intermedium）杂种后代的抗白粉病基因Pm40，被定位在小麦7BS 染色体上，对Bgt 具有广谱和持久的抗性。通过细胞学研究，并未在Pm40 的载体品种中发现大片段外缘染色体。过去几年的研究发现，Pm40 的载体品种具有优良的农艺性状。因此，我们相信在未来的育种工程中，Pm40 将会在Pm21 的抗性被克服之后起巨大的作用。另外，Pm21 和Pm40 都来源于外缘物种，这暗示着外源基因的抗性可能比小麦本身的基因更为持久和有效。

关键词： 小麦     白粉病     <i>Pm21i>     <i>Pm40i>     外源基因     内源抗性    

HTML PDF 收藏

标题 作者 时间 类型 操作

Approaching the binding between Cu(II) and aerobic granules by a modified titration and µ-XRF

Hongwei LUO,Longfei WANG,Zhonghua TONG,Hanqing YU,Guoping SHENG

期刊论文

Thermogravimetric kinetic analysis of

SUKARNI,SUDJITO,Nurkholis HAMIDI,Uun YANUHAR,I.N.G. WARDANA

期刊论文

Genomic and metabolomic analysis of with enhanced poly--glutamic acid production through atmospheric

期刊论文

CeO doping boosted low-temperature NH-SCR activity of FeTiO catalyst: A microstructure analysis and reaction

期刊论文

Analysis of flow over backward facing step with transition

Dwarikanath RATHA,Arindam SARKAR

期刊论文

A systematic approach in load disaggregation utilizing a multi-stage classification algorithm for consumer electrical appliances classification

Chuan Choong YANG, Chit Siang SOH, Vooi Voon YAP

期刊论文

Elasto-plastic fatigue crack growth analysis of plane problems in the presence of flaws using XFEM

SHEDBALE,I. V. SINGH,B. K. MISHRA

期刊论文

802.11i认证协议可验安全性形式化分析

宋宇波,胡爱群,姚冰心

期刊论文

Analysis of antibiotic resistance of

Yangyang Yu, Xiaolin Zhu, Guanlan Wu, Chengzhi Wang, Xing Yuan

期刊论文

Life-cycle assessment and techno-economic analysis of the production of wood vinegar from stem: a case

期刊论文

Regulatory mechanism and functional analysis of

null

期刊论文

Application of StrucGP in medical immunology: site-specific -glycoproteomic analysis of macrophages

期刊论文

Panoramic variation analysis of a family with neurodevelopmental disorders caused by biallelic loss-of-function

期刊论文

Development of a new method for RMR and Q classification method to optimize support system in tunneling

Asghar RAHMATI,Lohrasb FARAMARZI,Manouchehr SANEI

期刊论文

抗白粉病基因 <i>Pm40i> 在我国“后 <i>Pm21i> 时代”小麦育种中的重要作用

唐圣雯,胡玉亭,钟胜福,罗培高

期刊论文